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I hope you read through the prior lesson carefully and thereby learnt what the COVID-19 virus is and an understanding of the basics of how viruses cause diseases. If not, please go back and study Lesson 1 Principles of COVID-19 disease, and Lesson 2 What is Coronavirus COVID-19, and then come back here.
Viruses do not reproduce like other organisms. There are no male & female viruses. Viruses need a living organism (animals, humans) which have living cells in them (called hosts), into which viruses enter and then reproduce by use of the genetic material in these hosts and then continue to proliferate and damage the target organ.
Spread of viruses between the human population happens via any medium of common contact between two or more people: such as air, water, plants, animals, parasites etc.
Here is the sequential process of how a virus reproduces, spreads and damages a target organ.
There are 7 important biochemical processes involved in the replication of a virus once it enters a living organism:
This is the very first step. The virus first moves into the human body and adsorbs to the first layer of immunity – the mucous membrane.
If the immunity of the individual is strong (or adapted to the specific virus), the virus is destroyed at this layer itself and eliminated. If the immunity is not strong then the virus passes through this barrier and moves on to step 2 – Attachment.
Quick insight: People having low vitamin C & D have weak immunity at the mucous membrane level which thereby puts them at risk to allow the virus to enter into the target organ. Patients with chronic disease in most cases have low Vitamin C & D, including deficiencies in other essential nutrients.
Here the virus attaches to the target organ by attaching to the specific receptors of the target organ cell, which thereby allows it entry into the cell – step 3.
In the case of the novel covid-19 virus, once it passes through the mucous membrane (first immunity barrier) of the respiratory system, it attaches to the wall of the type II pneumocytes (lung cells) by its spike proteins called the S-spike to the receptor called the ACE-2.
Once the virus attaches/binds to the cell surface receptor (lung cell in case of COVID-19), it then is allowed entry into the cell.
The best analogy for comprehension of this step is a door-lock-key-entry analogy. – Viruses have a protein coat with spike proteins (like antennas) on their surface which function like keys with a specific pattern, and the organ-cells have receptors on their surface which function like locks with a specific pattern. If any virus has the precise key pattern (spike proteins) to attach to the lock of the organ cell (receptors), it can then get entry into the cell.
After entry, the process of uncoating takes place where the viral protein coat (outer protein coat-layer of the virus) is removed by enzymes in the cell. This process of uncoating exposes the genetic material of the virus which in most cases is an RNA (ribo-nucleic acid).
The viral RNA is then used by a polymerase enzyme (an enzyme inside the cell used for building proteins for cellular regeneration) to synthesize new RNA strands of the called mRNA (messenger ribonucleic acid).
The newly synthesized RNA strands (virus gene) are then further used to form the genomic components of the newer copies of the virus which are done in step 6.
The organ cell’s internal ribosomal machinery (a bio-mechanism used to produce components of a cell for cellular regeneration & reproduction) is then utilised for protein synthesis to build all the proteins (components) to assemble the new virus.
This process is called translation. The mRNA is translated by the ribosomes and two types of proteins called the structural and non-structural proteins are synthesised and then assembled. The capsid protein coat and S-strands are synthesised at this stage.
Once the protein components of the virus and the RNA strands are built, the process of assembly of these components is done to form a new virus particle.
After the virion assembly, the fully matured viruses are prepared to leave the cells to mark the end of the process of replication.
These newly manufactured viruses leave the cell abruptly or by the process of budding away from the cell surface membrane. In this abrupt process the virus destroys the cellular structure which causes cellular breakdown and thereby organ malfunction and eventually organ failure.
Now that you learn the general process of how a virus enters, reproduces and then damages an organ, here is now the process of how the novel coronavirus COVID-19 reproduces and damages the organs in the respiratory system.
A healthy immune system can eliminate the virus at any step of the chain of infection whereas a weaker one fails to do so. The body tries to generate an intense immune reaction in order to fight with the infection and thus only a robust immune system can do that.
The virus is seen to also spread into other organs (not just the lungs) and produce organ damage but there are no casualties reported so far in such scenarios.
In Heal Within™, our focus and relentless pursuit is to help our patients achieve these Three Primary Objectives.
To learn the details of the what & why of these end-objectives, and understand why it is crucial that you establish this in your mind first prior to starting any healthcare treatment or prevention program, please go to Lesson 1 – First, Establish Your End-Objectives (if you not already done so).
We use an advanced Integrated & Holistic Treatment approach and have consistently helped numerous patients with all forms of diseases achieve these Three Primary Objectives. Moreover there has not been a single reported case of COVID-19 from any of our patients; our programs have helped all our patients optimise their immunity and protect themselves from this viral infection.
If you had COVID-19 & already treated and now seek to prevent a recurrence, or if you have no infection at the moment but want to optimise your immunity so to prevent being infected in the future, then just send us an enquiry or come visit our centre to see how we can help.
We have both: a comprehensive service in-clinic program, and a DIY-at-home program (i.e. do it yourself at home program). To learn more about our programs please go to the program-details web-page, the link to which is below.
Got questions? Want to learn more? Scroll down here
Dr Lee Cheng Lok is the founder & medical director in Heal Within™. This lesson series is a part of his mission to educate & heal patients with chronic diseases, and prevent others from experiencing chronic disease by using an Integrated & Holistic approach.
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